Evidence verdicts
36 supplements and protocols, one row each. Each row carries one verdict, worked out from every counted mention on the record. 8 of 36 have not enough evidence yet.
Strong consensus for 6Leaning for 20Mixed 1Conflicting 1Leaning against 0Strong consensus against 0Not enough evidence 8
positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.
Creatine is worth taking.
10 sources: 7 positive, 2 partly, 1 neutral
Regular sauna use is worth doing for health.
10 sources: 6 positive, 4 partly
Zone 2 exercise is worth doing.
9 sources: 7 positive, 2 partly
Ashwagandha is worth taking.
4 sources: 3 positive, 1 partly
Glycine is worth taking.
4 sources: 3 positive, 1 partly
Sleep is the most important pillar of health and longevity.
4 sources: 3 positive, 1 partly
Fasting is worth doing for health.
31 sources: 11 positive, 20 partly
Deliberate cold exposure is worth doing.
16 sources: 10 positive, 5 partly, 1 negative
GLP-1 drugs are worth taking for people with obesity.
15 sources: 5 positive, 8 partly, 2 negative
Omega-3 supplements are worth taking.
15 sources: 3 positive, 12 partly
Probiotic supplements or fermented foods are worth taking.
15 sources: 1 positive, 14 partly
Vitamin B12 supplements are worth taking.
12 sources: 12 partly
Vitamin D supplements are worth taking.
12 sources: 4 positive, 5 partly, 2 neutral, 1 negative
Caffeine is worth using.
11 sources: 11 partly
Melatonin is worth taking for sleep.
8 sources: 2 positive, 4 partly, 1 neutral, 1 negative
Curcumin is worth taking.
7 sources: 3 positive, 3 partly, 1 negative
Electrolyte supplements are worth taking.
7 sources: 3 positive, 4 partly
Folate supplements are worth taking.
6 sources: 6 partly
Magnesium supplements are worth taking.
6 sources: 2 positive, 4 partly
Extra virgin olive oil is worth eating every day.
5 sources: 2 positive, 3 partly
CoQ10 is worth taking.
4 sources: 1 positive, 3 partly
Iron supplements improve health only in people whose iron is low.
4 sources: 1 positive, 2 partly, 1 neutral
Zinc supplements are worth taking.
4 sources: 1 positive, 3 partly
Berberine is worth taking.
3 sources: 3 partly
NAC is worth taking.
3 sources: 2 positive, 1 partly
Selenium supplements are worth taking.
3 sources: 1 positive, 2 partly
Too few counted mentions to call either way. Each verdict updates as more mentions are counted.
Metformin slows aging in people without diabetes.
3 sources: 1 partly, 1 neutral, 1 negative
Vitamin C supplements are worth taking.
3 sources: 2 partly, 1 neutral
Garlic is worth taking for health.
2 sources: 2 positive
Vitamin K2 is worth taking.
2 sources: 2 positive
Astaxanthin is worth taking.
1 source: 1 positive
Glutathione supplements are worth taking.
1 source: 1 positive
Low-dose rapamycin slows aging in healthy people.
1 source: 1 partly
Sulforaphane is worth taking.
1 source: 1 partly
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Cite as: Precis Consensus Matrix, 36 topics, precis.health/tools/consensus-matrix, updated 29 June 2026.
This consensus matrix is free. A free account opens the dose, form and timing claims behind every row, each with its verdict and receipts. Pro adds the chat that answers from 3,700+ hours of recorded interviews with 370+ researchers and doctors, plus 18,100+ research studies.
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How this is built: Built from 3,700+ hours of recorded interviews with 370+ researchers and doctors, plus 18,100+ research studies. Updated Oct 5, 2026. Each verdict is computed from every counted mention of the topic's main claim, never written by hand. Click a row to read the full report with its receipts.