Consensus Report
Vitamin K2
Moderate Consensus
out of 5
Based on 11 videos (16 hours analyzed) across the experts · Updated 2026-03-21
Expert Positions
The Verdict
3 of 5 experts recommend vitamin K2 — Hyman always pairs it with D3, Patrick provides the deepest mechanism via Triage Theory, and Johnson takes D3K2 daily. Attia conspicuously omits K2 from his bone health 'big three' (calcium, D3, magnesium) despite extensive bone health content. Huberman has zero coverage.
Where They Disagree
Attia defines bone health micronutrients as calcium + D3 + magnesium only, conspicuously omitting K2 across 5+ dedicated bone health episodes — while Hyman, Patrick, and Johnson all include K2 in their calcium metabolism framework.
Hyman treats D3+K2 as inseparable foundational supplements, while Attia and Huberman supplement with D3 without mentioning K2 — suggesting they either view K2's evidence as insufficient or consider it unnecessary when other bone health factors are addressed.
+ 2 more disagreements in the full report
About This Analysis
This consensus report on Vitamin K2 is based on 11 videos (16 hours analyzed) from five longevity experts: Andrew Huberman, Peter Attia, Rhonda Patrick, Bryan Johnson, and Mark Hyman. Each expert's position was independently analyzed from their published video content, including lectures, podcast episodes, and Q&A sessions with 1,000+ guest scientists.
The full report includes 7 key findings, dosage and protocol details, expert deep dives with direct video citations and timestamps, risk considerations, and related supplement synergies.
Frequently Asked Questions
Should you take vitamin K2 with vitamin D3?
Yes — the three experts who cover K2 all pair it with D3. Hyman calls them inseparable and never recommends D3 alone; Johnson takes a combined D3K2 daily; Patrick explains that K2 directs the calcium D3 absorbs into bones rather than arteries. Attia omits K2 from his bone-health protocol and Huberman does not cover it.
What is the best form of vitamin K2 — MK-7 or MK-4?
MK-7 (menaquinone-7) is the most common supplemental form because it has a far longer half-life — days versus hours for MK-4 — so once-daily dosing keeps blood levels stable, while MK-4 needs several doses a day. The richest food source of K2 is natto, followed by hard cheeses, egg yolks, and grass-fed butter.
How much vitamin K2 should you take per day?
100–200mcg of MK-7 daily is the commonly cited supplemental dose. No expert names an exact K2 dose in the analyzed videos — Hyman and Johnson take it inside a combined D3/K2 supplement. There is no established RDA for K2 specifically; the 90–120mcg/day RDA covers total vitamin K.
Is vitamin K2 safe to take with blood thinners like warfarin?
No — anyone on warfarin or another vitamin K antagonist should not supplement K2 without physician supervision, because it can interfere with the medication and affect INR. Patrick notes that warfarin works by blocking vitamin K recycling, which is also why it worsens arterial calcification risk.
Why don't all longevity experts recommend vitamin K2?
Two of the five don't cover it: Attia deliberately omits K2 from his bone-health 'big three' (calcium, D3, magnesium) across 5+ episodes, and Huberman never mentions it. The likely reason is evidence maturity — K2's mechanism is well understood, but the clinical-outcome trials for fracture and cardiovascular reduction are still emerging, unlike the deeper evidence base for vitamin D or omega-3.
Common Questions
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