Berberine

Expert Positions

Andrew Huberman

Mentions but Personally Avoids

Peter Attia

Uses Clinically for LDL

Rhonda Patrick

No Direct Coverage

Bryan Johnson

No Direct Coverage

Mark Hyman

Recommends as AMPK Activator

The Verdict

Berberine is a polarizing supplement among the 5 experts. Attia uses it clinically for LDL management in select patients but prefers metformin for glucose control. Huberman mentions it as a glucose disposal agent but personally avoids it for longevity. Hyman views it positively as an AMPK activator and gut antimicrobial. Patrick and Johnson have no direct coverage.