Consensus Report

Folate

2.8

Moderate Consensus

out of 5

Based on 182 videos (134 hours analyzed) across 5 experts · Updated 2026-03-23

Expert Positions

Andrew Huberman
Andrew Huberman
Mentions Through Guest Experts
Peter Attia
Peter Attia
Includes in Personal Protocol
Rhonda Patrick
Rhonda Patrick
Recommends for MTHFR Carriers
Bryan Johnson
Bryan Johnson
Minimal Coverage
Mark Hyman
Mark Hyman
Strongly Recommends Methylfolate

The Verdict

3 of 5 experts actively recommend folate supplementation — but context matters enormously. Hyman is the strongest advocate, recommending methylfolate across dozens of videos for brain health, fertility, and depression. Patrick and Attia both supplement with methylfolate specifically to manage homocysteine levels, with Attia including it in his personal stack. Huberman and Johnson mention folate only in passing through guest experts. The key nuance: all experts who discuss it insist on the methylated form (5-MTHF), not synthetic folic acid.

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