Supplement Comparisons
The supplement aisle sells the form, not the evidence. These 11 comparisons cut to what five longevity experts actually take — and where they disagree — each cited to the video and minute.
Same molecule — the label word doesn't matter; buy fully-chelated (not oxide-buffered)
They're the same compound. 'Bisglycinate' is the chemically precise name — one magnesium bound to two ('bis') glycine molecules — and 'glycinate' is the everyday shorthand for exactly the...
Glycinate for daily use & sleep; Citrate if you want the laxative effect
Take glycinate for daily magnesium, sleep, and calm — it's the form Patrick, Hyman, and Huberman actually use. Choose citrate mainly if you also want help with constipation; its laxative...
Glycinate for daily use & absorption; Oxide only for its cheap laxative effect
Take glycinate for daily magnesium, sleep, and calm — it's well-absorbed and gentle on the stomach. Magnesium oxide is the cheapest form but poorly absorbed; most of it passes through and...
Glycinate for daily use, Threonate for brain-specific goals
Take glycinate (or malate) for your daily magnesium needs. Add threonate only if you want targeted cognitive support — but don't count it toward your daily requirement.
NAD+ is the goal; NMN is the (still-unproven) oral precursor — experts are mostly skeptical
NAD+ is the coenzyme your cells actually run on; NMN is a precursor you take to raise it — because oral NAD+ is a large molecule that's poorly absorbed and broken down in the gut. So it...
No consensus — most experts are skeptical or cautious
This is one of the most divisive topics. Attia says skip both — exercise and fasting boost NAD naturally. If you do supplement, NR has better safety data (Patrick), but NMN may have a...
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