Evidence verdicts
44 supplements, tiered by one verdict each. The verdict is worked out from every counted mention on the record, never from a score. 18 of 44 have not enough evidence yet.
Strong consensus for 3Leaning for 21Mixed or conflicting 2Leaning or strong against 0Not enough evidence 18
positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.
Enough counted mentions, from enough sources, and nearly all of them point the same way.
Full Report
Strong consensus for
10 sources: 7 positive, 2 partly, 1 neutral
Full Report
Strong consensus for
4 sources: 3 positive, 1 partly
Full Report
Strong consensus for
4 sources: 3 positive, 1 partly
Most counted mentions point the same way, but the evidence is thinner or less one-sided.
15 sources: 3 positive, 12 partly
15 sources: 1 positive, 14 partly
12 sources: 12 partly
12 sources: 4 positive, 5 partly, 2 neutral, 1 negative
11 sources: 11 partly
8 sources: 2 positive, 4 partly, 1 neutral, 1 negative
7 sources: 3 positive, 3 partly, 1 negative
7 sources: 3 positive, 4 partly
6 sources: 6 partly
6 sources: 2 positive, 4 partly
6 sources: 2 positive, 4 partly
5 sources: 1 positive, 4 partly
5 sources: 2 positive, 3 partly
5 sources: 1 positive, 3 partly, 1 negative
4 sources: 1 positive, 3 partly
4 sources: 1 positive, 2 partly, 1 neutral
4 sources: 1 positive, 3 partly
3 sources: 3 partly
3 sources: 2 positive, 1 partly
3 sources: 1 positive, 2 partly
3 sources: 1 positive, 2 partly
The counted mentions point in different directions.
Too few counted mentions to call either way.
3 sources: 2 partly, 1 neutral
2 sources: 2 partly
2 sources: 1 partly, 1 neutral
2 sources: 2 positive
2 sources: 2 positive
2 sources: 2 positive
2 sources: 1 positive, 1 partly
2 sources: 2 positive
1 source: 1 partly
1 source: 1 positive
1 source: 1 positive
1 source: 1 partly
1 source: 1 partly
1 source: 1 positive
No counted mention yet
No counted mention yet
No counted mention yet
No counted mention yet
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This tier list is free. A free account opens the dose ranges, forms (glycinate or threonate, for example) and timing for every supplement above.
Prescription drugs (rapamycin, metformin) and protocols (fasting, sauna, cold exposure, zone 2) are left out of this list.
How this is built: Built from 3,700+ hours of recorded interviews with 370+ researchers and doctors, plus 18,100+ research studies. Updated Oct 5, 2026. Each mention is read and marked positive, partly, neutral or negative, and the verdict is computed from every counted mention. Individual needs vary. This is not medical advice.