Evidence verdicts
44 supplements, tiered by one verdict each. The verdict is worked out from every counted mention on the record, never from a score. 9 of 44 have not enough evidence yet.
Strong consensus for 3Leaning for 28Mixed or conflicting 4Leaning or strong against 0Not enough evidence 9
positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.
Enough counted mentions, from enough sources, and nearly all of them point the same way.
Full Report
Strong consensus for
11 sources: 8 positive, 2 partly, 1 neutral
Full Report
Strong consensus for
8 sources: 6 positive, 2 partly
Full Report
Strong consensus for
5 sources: 4 positive, 1 partly
Most counted mentions point the same way, but the evidence is thinner or less one-sided.
30 sources: 15 positive, 14 partly, 1 negative
27 sources: 6 positive, 17 partly, 4 negative
17 sources: 7 positive, 10 partly
15 sources: 2 positive, 11 partly, 2 negative
15 sources: 4 positive, 11 partly
14 sources: 12 partly, 2 negative
13 sources: 3 positive, 9 partly, 1 negative
12 sources: 6 positive, 6 partly
10 sources: 6 positive, 4 partly
10 sources: 1 positive, 9 partly
9 sources: 4 positive, 4 partly, 1 negative
9 sources: 3 positive, 5 partly, 1 negative
9 sources: 2 positive, 6 partly, 1 negative
9 sources: 4 positive, 4 partly, 1 negative
8 sources: 3 positive, 5 partly
7 sources: 1 positive, 5 partly, 1 negative
6 sources: 3 positive, 3 partly
6 sources: 6 partly
6 sources: 6 partly
6 sources: 3 positive, 3 partly
6 sources: 2 positive, 4 partly
5 sources: 2 positive, 2 partly, 1 negative
5 sources: 1 positive, 4 partly
5 sources: 1 positive, 3 partly, 1 neutral
4 sources: 1 positive, 3 partly
3 sources: 2 positive, 1 partly
3 sources: 1 positive, 2 partly
3 sources: 1 positive, 2 partly
The counted mentions point in different directions.
9 sources: 6 partly, 3 negative
9 sources: 2 positive, 3 partly, 4 negative
7 sources: 3 positive, 2 partly, 2 negative
7 sources: 2 positive, 2 partly, 3 negative
Too few counted mentions to call either way.
2 sources: 1 positive, 1 partly
2 sources: 2 partly
2 sources: 1 positive, 1 negative
2 sources: 1 positive, 1 partly
2 sources: 2 positive
1 source: 1 positive
1 source: 1 partly
No counted mention yet
No counted mention yet
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This tier list is free. A free account opens the dose ranges, forms (glycinate or threonate, for example) and timing for every supplement above.
Prescription drugs (rapamycin, metformin) and protocols (fasting, sauna, cold exposure, zone 2) are left out of this list.
How this is built: Built from 3,700+ hours of recorded interviews with 380+ researchers and doctors, plus 87,700+ research studies. Updated Oct 27, 2026. Each mention is read and marked positive, partly, neutral or negative, and the verdict is computed from every counted mention. Individual needs vary. This is not medical advice.