Goal-Based Guide
The liver is your body's primary detoxification organ. These supplements have the strongest expert consensus for supporting liver function and glutathione production.
3 of 5 experts actively recommend NAC supplementation. Hyman is the strongest advocate by far, recommending NAC across 24 videos for glutathione support, detoxification, liver health, immune function, and brain health. Johnson includes NAC as a core pill in his daily Blueprint stack. Huberman and a guest (Dr. Seheult) discuss NAC for immune support and cold prevention. Attia and Patrick have no direct NAC coverage in analyzed videos.
3 of 5 experts actively discuss sulforaphane, with Patrick being the dominant authority. Patrick has dedicated multiple videos to sulforaphane's Nrf2 activation, cancer prevention, and detoxification benefits, and personally consumes broccoli sprouts daily. Huberman covers sulforaphane through guest episodes with Patrick, endorsing it for detoxification and liver support. Hyman references sulforaphane frequently as a phytochemical within broader food-as-medicine discussions. Attia and Johnson have no direct sulforaphane coverage in analyzed videos.
Supporting the body's detoxification pathways:
Taking NAC without supporting nutrients. Hyman recommends pairing with alpha-lipoic acid, B vitamins, selenium, and milk thistle.
Ignoring dietary sources of sulfur. Garlic, onions, and cruciferous vegetables naturally boost glutathione production.
Not addressing the root cause of liver stress: excess alcohol, processed foods, and environmental toxins.
This page shows you which supplements researchers agree on for liver health. Pro unlocks the specific protocols — exact dosages, timing, form recommendations, and interactions — so you can actually execute.
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