Goal-Based Guide
Omega-3 is the clearest anti-inflammatory pick, with vitamin D and curcumin behind it. NAC and sulforaphane come up too, but from only a few sources. Here's what each one does.
Chronic low-grade inflammation, sometimes called 'inflammaging', is a root driver of most chronic diseases. These supplements have the most support for reducing it.
Ranked by the verdict on whether each supplement works, worked out from every counted mention. Each dot is one source: a researcher or a study.
positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.
Omega-3 supplements are worth taking.
17 sources: 7 positive, 10 partly
Vitamin D supplements are worth taking.
12 sources: 6 positive, 6 partly
Curcumin is worth taking.
3 sources: 2 positive, 1 partly
NAC is worth taking.
2 sources: 2 positive
Sulforaphane is worth taking.
1 source: 1 partly
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Targeting chronic inflammation through well-studied pathways:
This page shows you which supplements researchers agree on for inflammation. A free account opens the dose, form and timing for each supplement, with the interactions to watch. Pro adds chat answers drawn from 3,700+ hours of recorded interviews with 380 researchers and doctors, plus 48,500+ research studies, each one cited.
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