Goal-Based Guide

Best Supplements for Anxiety

Two supplements have meaningful support for anxiety: ashwagandha and magnesium. It's a short list, and short for a reason: the rest of the category barely comes up. Here's what the evidence says.

Anxiety is one of the most common reasons people reach for supplements. These are the compounds with the most support for stress and cortisol reduction.

Verdicts are worked out from what researchers say in public videos. Not medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement.

Top Supplements for Anxiety

Ranked by the verdict on whether each supplement works, worked out from every counted mention. Each dot is one source: a researcher or a study.

positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.

  1. Magnesium

    Strong consensus for

    Magnesium supplements are worth taking.

    8 sources: 6 positive, 2 partly

    8 sources: 6 positive, 2 partly

  2. Ashwagandha

    Leaning for

    Ashwagandha is worth taking.

    6 sources: 3 positive, 3 partly

    6 sources: 3 positive, 3 partly

Precis is not affiliated with or endorsed by YouTube or by any researcher, show or publisher we quote. We take no sponsorship, ad or affiliate money, and every verdict is our own review of what was said. How we stay independent

The Stress & Anxiety Stack

Cortisol management, from protocols on record:

  • Ashwagandha - 300mg twice daily for cortisol reduction; cycle off after 30 days
  • Magnesium glycinate - 300-400mg in the evening for GABA activity and muscle relaxation
  • L-Theanine - 100-200mg for calming without sedation
  • Apigenin - 50mg in the evening alongside ashwagandha for cortisol

Common Mistakes

  1. Taking ashwagandha continuously without cycling. The protocol on record is 30 days on, then off.
  2. Using melatonin for anxiety-related sleep issues. Behavioral tools and a magnesium-apigenin-theanine stack come first.
  3. Not monitoring thyroid and hormonal markers when taking ashwagandha. It can affect testosterone and thyroid function.
  4. Ignoring root-cause interventions: sleep, exercise, and stress management practices.

Know what to take. Now learn exactly how.

This page shows you which supplements researchers agree on for anxiety. A free account opens the dose, form and timing for each supplement, with the interactions to watch. Pro adds chat answers drawn from 3,700+ hours of recorded interviews with 380 researchers and doctors, plus 48,500+ research studies, each one cited.

Cancel anytime

Other Goal Guides