Goal-Based Guide
Only a handful of supplements hold up for longevity: omega-3, creatine, probiotics, magnesium and vitamin D. Beyond that short list, the sources disagree. Here's what each one does.
Longevity supplements are about healthspan, the years you live in good health. Across the researchers we track, including 100-plus-pill regimens, only a short list holds up. Here are the supplements with the most support, and where the evidence stops. (We don't sell any of them.)
Ranked by the verdict on whether each supplement works, worked out from every counted mention. Each dot is one source: a researcher or a study.
positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.
Creatine is worth taking.
11 sources: 8 positive, 2 partly, 1 neutral
Magnesium supplements are worth taking.
8 sources: 6 positive, 2 partly
Probiotic supplements or fermented foods are worth taking.
30 sources: 15 positive, 14 partly, 1 negative
Omega-3 supplements are worth taking.
17 sources: 7 positive, 10 partly
Vitamin D supplements are worth taking.
12 sources: 6 positive, 6 partly
Precis is not affiliated with or endorsed by YouTube or by any researcher, show or publisher we quote. We take no sponsorship, ad or affiliate money, and every verdict is our own review of what was said. How we stay independent
The supplements with the most support for healthspan:
This page shows you which supplements researchers agree on for longevity. A free account opens the dose, form and timing for each supplement, with the interactions to watch. Pro adds chat answers drawn from 3,700+ hours of recorded interviews with 380 researchers and doctors, plus 48,500+ research studies, each one cited.
Cancel anytime