Expert Answer
Quick Answer
100-200mg of ubiquinol daily for general support (Hyman). 200-400mg for immune recovery or chronic fatigue. Anyone on statins should strongly consider CoQ10 — statins directly block CoQ10 production.
Strong Consensus
on CoQ10 overall
100-200mg ubiquinol daily. 200-400mg for recovery. Essential for statin users. Discusses across 23 videos.
Lists CoQ10 for fertility optimization alongside L-carnitine, omega-3s, and zinc.
Includes CoQ10 in Blueprint protocol for oral health and gum rejuvenation.
CoQ10 dosage comes primarily from Hyman, who covers it across 23 videos. For general mitochondrial support: 100-200mg of ubiquinol (the reduced, active form) daily alongside alpha-lipoic acid, acetyl-L-carnitine, and B vitamins.
For immune recovery or chronic fatigue: 200-400mg daily. For statin users: this is the most critical use case, as statins block CoQ10 synthesis alongside cholesterol.
Form matters: ubiquinol is preferred over ubiquinone for better absorption. Take with a fat-containing meal. Also recommended for fertility by Huberman.
Hyman strongly recommends it. Statins block HMG-CoA reductase, inhibiting both cholesterol and CoQ10 production, often causing muscle pain and fatigue.
This page covers what researchers agree on. Pro gives you the specific dosages, timing schedules, and interaction warnings they each recommend — with video citations you can verify.
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