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Quick Answer
100-200mg of ubiquinol daily for general support (Hyman). 200-400mg for immune recovery or chronic fatigue. Anyone on statins should strongly consider CoQ10 - statins directly block CoQ10 production.
Strong Consensus
on CoQ10 overall
100-200mg ubiquinol daily. 200-400mg for recovery. Essential for statin users. Discusses across 23 videos.
Lists CoQ10 for fertility optimization alongside L-carnitine, omega-3s, and zinc.
Includes CoQ10 in Blueprint protocol for oral health and gum rejuvenation.
CoQ10 dosage comes primarily from Hyman, who covers it across 23 videos. For general mitochondrial support: 100-200mg of ubiquinol (the reduced, active form) daily alongside alpha-lipoic acid, acetyl-L-carnitine, and B vitamins.
For immune recovery or chronic fatigue: 200-400mg daily. For statin users: this is the most critical use case, as statins block CoQ10 synthesis alongside cholesterol.
Form matters: ubiquinol is preferred over ubiquinone for better absorption. Take with a fat-containing meal. Also recommended for fertility by Huberman.
Hyman strongly recommends it. Statins block HMG-CoA reductase, inhibiting both cholesterol and CoQ10 production, often causing muscle pain and fatigue.
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