Expert Answer
Quick Answer
Creatine monohydrate. Attia calls it "the gold standard" and says expensive alternative forms offer no added benefit. Buy a third-party-tested (e.g. NSF-certified) monohydrate powder and skip gummies, which degrade. Huberman, Patrick, and Hyman all specify monohydrate too.
Universal Consensus
on Creatine overall
Calls creatine monohydrate the gold standard for strength, hypertrophy, and cognition; says expensive alternative forms add no efficacy; recommends NSF-certified powder and avoiding gummies.
Consistently specifies creatine monohydrate at 5g/day, and discusses higher-dose monohydrate for brain and TBI contexts — never a novel form.
Endorses the monohydrate form and its well-established safety profile, citing work with Darren Candow and Stuart Phillips.
Recommends creatine monohydrate for muscle, cognition, and sleep support, notably for women who produce less endogenously.
Includes creatine at 5g/day in the Blueprint stack, though he doesn't specify monohydrate vs other forms.
This is one of the least controversial questions in supplements: the best form of creatine is monohydrate, and the fancier forms are a waste of money.
Attia is the most direct. He calls creatine monohydrate "the gold standard" for strength, hypertrophy, and potential cognitive benefits, and states that the more expensive alternative forms offer no additional efficacy. He repeats the point with Layne Norton — 5g is enough to saturate muscle without resorting to pricier, unnecessary forms. The other experts independently reach for the same word: Huberman specifies creatine monohydrate at 5g/day (and discusses higher-dose monohydrate in brain and TBI contexts), Patrick endorses monohydrate and its safety profile, and Hyman recommends monohydrate especially for women, who produce less creatine endogenously.
Where the real decision lies is quality, not chemistry. Attia's practical advice is to prioritize a third-party-tested, NSF-certified creatine monohydrate powder to ensure purity, and to avoid creatine gummies, which suffer from manufacturing challenges and degradation that leave them underdosed. That's the same theme that runs through the whole "is this supplement any good" question — with a commodity ingredient like monohydrate, you're really buying verified purity.
One clarification on "Creapure." Creapure is a branded, German-made, NSF-certified grade of creatine monohydrate — a purity spec, not a different or better molecule. It comes up in reference material (the Diary of a CEO channel recommends it for perimenopausal women), but none of the five consensus experts single it out by name. And a note on the "alternative forms" — the experts say expensive alternatives add nothing, but they don't individually name-check HCl, ethyl ester, or buffered creatine in the material we analyzed, so treat those as illustrative examples of the pricier forms to skip.
Monohydrate. Attia calls creatine monohydrate the gold standard and says expensive alternative forms offer no additional efficacy. Huberman, Patrick, and Hyman all specify monohydrate as well.
No added benefit over monohydrate, per Attia, who says the expensive alternative forms don't improve on it. He does not individually name those forms in our corpus — they're examples of the pricier options to skip.
Creapure is a branded, NSF-certified, German-made grade of creatine monohydrate — a purity spec, not a different molecule. It appears in reference material, but none of the five consensus experts single it out.
Powder. Attia recommends NSF-certified monohydrate powder and warns against gummies, which degrade and end up underdosed; capsules can also be underdosed.
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Full Creatine Consensus Report
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