other primary study · 2021
“Thus, those who quit smoking at ages 15 to 34, 35 to 44, 45 to 54, and 55 to 64 years avoided an estimated 100%, 89%, 78%, and 56% of the excess cancer mortality risk associated with continued smoking, respectively (Figure 2).”
Association of Smoking Initiation and Cessation Across the Life Course and Cancer Mortality: Prospective Study of 410 000 US Adults. JAMA Oncol
Who: US adults aged 25-79 in the National Health Interview Survey 1997-2014 linked to the National Death Index (mean age 48, 56% female)
PMID 34673892
other primary study · 2017 · read from the abstract
“CONCLUSIONS: Our study suggests that longer duration of smoking cessation may attenuate the risk of cancer in both men and women, and that even heavy smokers (more than 20 pack-years) were found to benefit from quitting smoking.”
Smoking cessation and subsequent risk of cancer: A pooled analysis of eight population-based cohort studies in Japan. Cancer Epidemiol
Who: participants of eight population-based prospective cohort studies in Japan
PMID 29102692
pooled analysis · 2024
“In conclusion, this meta-analysis of 65 studies from different countries showed that smoking cessation reduces the risk of HN cancer by about half, with a strong effect on the duration of cessation.”
Reduction of head and neck cancer risk following smoking cessation: a systematic review and meta-analysis. BMJ Open
Who: adults at risk of head and neck (oral, pharyngeal, laryngeal) cancer in case-control and cohort studies; current smokers as reference
PMID 39122405
pooled analysis · 2020 · read from the abstract
Not counted. Read from the abstract. It could change the badge, so it counts once read in full.
“At 5 YSQ, the percentage of reducible RR remaining was 57.2% (45.7-67.3%); at 10 years, it was 36.9% (28.3-47.9%); at 15 years, it was 26.7% (20.2-34.3%); and at 20 years, it was 19.7% (13.3-26.4%).”
Reexamining Rates of Decline in Lung Cancer Risk after Smoking Cessation. A Meta-analysis. Ann Am Thorac Soc
Who: prospective cohorts reporting lung cancer relative risks by years since quitting, from 20 countries and territories
PMID 32603182
other primary study · 2010
“Results Quitting tobacco smoking for 1–4 years resulted in a head and neck cancer risk reduction [OR 0.70, confidence interval (CI) 0.61–0.81 compared with current smoking], with the risk reduction due to smoking cessation after ≥20 years (OR 0.23, CI 0.18–0.31), reaching the level of never smokers.”
Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk. Int J Epidemiol
Who: pooled individual-level data from case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium
PMID 19805488
other primary study · 2024
“Smoking cessation significantly modified pack-years, where every year quit corresponded to a 1 − e (−0.0933) = 8.9% (95% CI 2.4%, 15.0%; p = 0.008) decreased excess risk of prior smoking.”
Excess pancreatic cancer risk due to smoking and modifying effect of quitting smoking: The Multiethnic Cohort Study. Cancer Causes Control
Who: Multiethnic Cohort participants aged 45-75 at enrollment (1993-1996) in California and Hawaii, five racial/ethnic groups
PMID 37924460
other primary study · 2013 · read from the abstract
“For the best-fitting analysis (S1), H was 9.93 (95% CI 9.31-10.60), but varied by sex (females 7.92, males 10.71), and age (<50years 6.98, 70+years 12.99).”
How rapidly does the excess risk of lung cancer decline following quitting smoking? A quantitative review using the negative exponential model. Regul Toxicol Pharmacol
Who: studies of at least 100 lung cancer cases comparing current smokers, former smokers by time quit, and never smokers
PMID 23764305