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Quick Answer
Huberman's protocol is 300mg twice daily (600mg total) of a standardized extract to lower cortisol, cycled off after about 30 days and monitored with bloodwork — the only specific ashwagandha dose any of the 5 experts give. Most standardized-extract studies use 300-600mg/day. Start at 300mg to assess tolerance.
Strong Consensus
on Ashwagandha overall
Recommends 300mg twice daily (600mg total) for cortisol reduction across 8 videos; the only expert to specify a cycling protocol — cycle off after ~30 days and monitor via bloodwork. Takes it in the evening with apigenin.
Includes ashwagandha in his personal nighttime routine alongside glycine and magnesium L-threonate, but does not publish a specific dose.
Includes it in his Blueprint stack for anxiety and sleep — but takes it in the morning, a direct timing disagreement with Huberman and Attia.
Recommends it as an adaptogen for adrenal support and stress resilience, often paired with rhodiola, magnesium, and B vitamins.
Does not cover ashwagandha directly in her analyzed videos.
Only one of the five experts gives a specific ashwagandha dose: Andrew Huberman recommends 300mg twice daily (600mg total) of a standardized extract to lower cortisol, and he's the most detailed voice on it across 8 videos. Two things make his protocol distinctive. First, he explicitly says to cycle off after about 30 days and monitor via bloodwork — the only expert to specify a cycling protocol. Second, he takes it in the evening, pairing it with apigenin for cortisol management.
Peter Attia includes ashwagandha in his personal nighttime routine alongside glycine and magnesium L-threonate but doesn't publish a specific dose. Mark Hyman recommends it as an adaptogen for adrenal support and stress resilience, often paired with rhodiola, magnesium, and B vitamins. Bryan Johnson includes it in his Blueprint stack — but notably takes it in the morning, a direct timing disagreement with Huberman and Attia. Rhonda Patrick doesn't cover ashwagandha herself.
On form, no expert specifies KSM-66 versus Sensoril; both are standardized extracts, and most clinical studies use 300-600mg/day of a standardized root extract. The practical protocol: start at 300mg once daily to assess tolerance, move toward 300mg twice daily if needed, take it in the evening for cortisol and sleep (or the morning if you follow Johnson's approach), and cycle off after about a month.
Huberman explicitly recommends cycling off after about 30 days and monitoring via bloodwork — the only expert to specify a cycling protocol.
Huberman and Attia take it in the evening for cortisol and sleep; Johnson takes it in the morning. It's a genuine timing disagreement — evening is the more common choice for stress and sleep.
300mg twice daily (600mg total) is Huberman's stated dose and sits within the range used in most standardized-extract studies. Start at 300mg to assess tolerance.
This page covers what researchers agree on. Pro gives you the specific dosages, timing schedules, and interaction warnings they each recommend — with video citations you can verify.
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