Timing Protocol

When to Take Ashwagandha

What researchers say about when, how and with what to take ashwagandha, and how strong the evidence is.

The verdict on Ashwagandha overall

Leaning for

Ashwagandha is worth taking.

6 sources: 3 positive, 3 partly

6 sources: 3 positive, 3 partly

Based on what researchers say in publicly available videos, not medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement.

Short answer

Evening, for cortisol and sleep (Andrew Huberman; Peter Attia), paired with apigenin to lower cortisol (Andrew Huberman). It is also taken in the morning in one daily stack (Bryan Johnson).

Full Protocol

Timing
Evening, for cortisol and sleep (Andrew Huberman; Peter Attia), paired with apigenin to lower cortisol (Andrew Huberman). It is also taken in the morning in one daily stack (Bryan Johnson).
Dosage
300mg twice daily (600mg total) (Andrew Huberman). Start at 300mg to check how you tolerate it.
Form
KSM-66 and Sensoril are both standardized extracts. KSM-66 is a full-spectrum root extract; Sensoril uses root and leaf.
Notes
Cycle off after 30 days (Andrew Huberman). Monitor with blood work, especially for effects on testosterone and thyroid. It is not for preventive daily use; apply it carefully, based on data (Andy Galpin, on Huberman Lab).

What the evidence says about timing

One verdict, worked out from every counted mention. One dot is one source: a researcher or a study. Tap a dot to see its receipt.

positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.

Not enough evidence

Ashwagandha taken in the evening lowers cortisol and improves sleep.

2 sources: 2 partly. Fewer than 3 sources so far.

Researchers say

2 partly

Studies show

No study counted yet.

11 more not counted · see why
The study cited could not be identified. 3
We could not tell what position it takes on this claim. 3
A host's remark inside an interview. 2
We could not tell where the evidence comes from. 2
No quote from the tape on record yet. 1
Show the receipts from 2 sources
  1. Mark Hyman, on The Dr. Hyman Show, at 17:45 Video · partly · Opinion

    “certain adap can be helpful like ashwag gandha at night can help with high cortisol at night help you get to sleep”

  2. Louisa Nicola, on Rangan Chatterjee's channel, at 11:06 Video · partly · Opinion

    “there are supplements that can help you really downregulate cortisol, such as ashwagandha.”

Where the sources disagree

Built from every credited researcher and cited study on each claim.

Leaning for

Ashwagandha is worth taking.

Supports it 3 sources
Partly 3 sources

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Timing is half the equation

You know when to take Ashwagandha. A free account opens the interaction warnings for your whole stack. Pro adds chat about your own situation, drawn from 3,700+ hours of recorded interviews with 380 researchers and doctors, plus 48,500+ research studies.

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