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Omega-3 fish oil absorbs better when taken with a meal containing fat.
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By Arun AgrahriLast reviewed
Short answer
With a meal that contains fat, for best absorption. The time of day does not matter. The fat in your meal helps emulsify the fish oil and improves the absorption of both EPA and DHA.
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Omega-3 fish oil absorbs better when taken with a meal containing fat.
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Omega-3 fish oil absorbs better when taken with a meal containing fat. Beyond that, the hour does not matter. Rhonda Patrick, on her own show, notes that omega-3 absorption climbs when you take it with dietary fat.
Peter Attia takes fish oil with meals and picks the triglyceride form over the ethyl ester form, because it absorbs better. Patrick adds a wrinkle about getting DHA into the brain. Krill oil and salmon roe carry DHA in phospholipid form, which the brain's MFSD2A transporter takes up more efficiently than standard fish oil.
Take it at breakfast or dinner, whichever meal has the fat. For higher amounts (2g+ EPA/DHA), split the dose across two meals to cut any fishy aftertaste.
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