Expert Answer

Does glycine help with sleep?

Glycine sleep glycine amino-acid
Based on expert consensus data from publicly available videos, not medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement.

Quick Answer

Yes - all 5 experts recognize glycine's sleep benefits. Attia supplements nightly alongside magnesium and ashwagandha. It works by lowering core body temperature. Huberman lists it as an optional addition to his sleep stack. 1-3g before bed.

4.0/5

Strong Consensus

on Glycine overall

What Researchers Say

Peter Attia
Peter Attia Strongly Agrees

Personally supplements glycine nightly alongside ashwagandha and magnesium L-threonate.

Andrew Huberman
Andrew Huberman Agrees

Lists glycine as optional for middle-of-night awakenings in his Sleep Toolkit.

Mark Hyman
Mark Hyman Agrees

Recommends glycine for sleep quality and nervous system relaxation.

Bryan Johnson
Bryan Johnson Strongly Agrees

Includes glycine in Blueprint longevity mix alongside creatine and CAKG.

Detailed Answer

Glycine is well-supported for sleep with buy-in from all five experts. Attia takes it nightly alongside ashwagandha and magnesium threonate. Huberman lists it as an optional addition for middle-of-night awakenings. Johnson includes it in his morning longevity mix. Hyman recommends it for sleep quality.

The mechanism: glycine lowers core body temperature to facilitate sleep onset. This is complementary to magnesium's GABA activity. Dosage: 1-3g before bed. Glycine has a naturally sweet taste and dissolves easily in water.

Glycine is also a precursor to glutathione (alongside NAC's cysteine) and a key amino acid in collagen, giving it multiple roles beyond sleep.

Related Questions

Can you take glycine with magnesium?

Yes. Attia's nighttime routine combines both glycine and magnesium L-threonate alongside ashwagandha.

More Questions About Glycine

Does magnesium help with sleep? Does ashwagandha actually work for stress and a... Why do I wake up at 3am even though I take magn...

Precis Pro

Get the exact protocol for Glycine

The answer above is the whole answer — every expert's position, where they disagree, and the timecode behind each one. Nothing on this page is held back.

Pro adds

  • The dose each expert actually names, and the form they name with it
  • Timing and what they say to take it with, or keep it away from
  • The interactions they flag by name
  • Chat across 3,500+ expert videos, with a timecode behind every answer

$9/mo · Cancel anytime

Full Glycine Consensus Report

See what all the experts agree and disagree on
All expert answers