Expert Answer

Does glycine help with sleep?

Glycine sleep glycine amino-acid
This content is based on expert analysis of publicly available videos, not medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement.

Quick Answer

Yes — all 5 experts recognize glycine's sleep benefits. Attia supplements nightly alongside magnesium and ashwagandha. It works by lowering core body temperature. Huberman lists it as an optional addition to his sleep stack. 1-3g before bed.

4.0/5

Strong Consensus

on Glycine overall

What Researchers Say

Peter Attia
Peter Attia Strongly Agrees

Personally supplements glycine nightly alongside ashwagandha and magnesium L-threonate.

Andrew Huberman
Andrew Huberman Agrees

Lists glycine as optional for middle-of-night awakenings in his Sleep Toolkit.

Mark Hyman
Mark Hyman Agrees

Recommends glycine for sleep quality and nervous system relaxation.

Bryan Johnson
Bryan Johnson Strongly Agrees

Includes glycine in Blueprint longevity mix alongside creatine and CAKG.

Detailed Answer

Glycine is well-supported for sleep with buy-in from all five experts. Attia takes it nightly alongside ashwagandha and magnesium threonate. Huberman lists it as an optional addition for middle-of-night awakenings. Johnson includes it in his morning longevity mix. Hyman recommends it for sleep quality.

The mechanism: glycine lowers core body temperature to facilitate sleep onset. This is complementary to magnesium's GABA activity. Dosage: 1-3g before bed. Glycine has a naturally sweet taste and dissolves easily in water.

Glycine is also a precursor to glutathione (alongside NAC's cysteine) and a key amino acid in collagen, giving it multiple roles beyond sleep.

Related Questions

Can you take glycine with magnesium?

Yes. Attia's nighttime routine combines both glycine and magnesium L-threonate alongside ashwagandha.

More Questions About Glycine

Get the exact protocol for Glycine

This page covers what researchers agree on. Pro gives you the specific dosages, timing schedules, and interaction warnings they each recommend — with video citations you can verify.

  • Expert-by-expert dosage breakdowns
  • Chat with 1000+ hours of research data
  • Video citations with timestamps you can check
Get Pro — $9/mo

Cancel anytime

Full Glycine Consensus Report

See what all 5 experts agree and disagree on