Expert Answer
Quick Answer
Yes. 4 of 5 researchers recommend magnesium for sleep. Huberman includes magnesium threonate (145mg) in his core sleep stack alongside apigenin (50mg) and theanine (100-400mg). Attia personally takes magnesium threonate in his evening routine.
Strong Consensus
on Magnesium overall
Includes magnesium threonate (145mg) in his foundational sleep stack alongside apigenin and theanine.
Takes magnesium threonate in his nighttime routine alongside glycine and ashwagandha.
Recommends magnesium for sleep support. Also recommends it for sleep improvement when quitting alcohol.
Magnesium is a core component of the most widely discussed sleep protocol in longevity science. Huberman's foundational sleep stack — magnesium threonate (145mg), apigenin (50mg), and L-theanine (100-400mg) — targets different sleep pathways: magnesium for GABA activity and muscle relaxation, theanine for calming without sedation, and apigenin for anxiety reduction.
Attia personally supplements with magnesium threonate in his evening routine alongside glycine and ashwagandha. Hyman recommends magnesium for sleep and also for sleep support when quitting alcohol.
The mechanism involves GABA receptor activation and muscle relaxation. Take 30-60 minutes before bed. Use threonate or glycinate form for sleep — not oxide.
Threonate and glycinate are the most recommended for sleep. Threonate crosses the blood-brain barrier; glycinate promotes relaxation.
This page covers what researchers agree on. Pro gives you the specific dosages, timing schedules, and interaction warnings they each recommend — with video citations you can verify.
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Full Magnesium Consensus Report
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