Answer

Do you need B12 supplements?

Vitamin B12 b12 methylation brain-health

Verdict

Leaning for

Vegans and people over 50 usually need to supplement B12.

5 sources: 5 partly

5 sources: 5 partly

By Arun AgrahriLast reviewed

Based on what researchers say in public interviews on YouTube. Educational only, not medical advice. Ask a qualified clinician before changing a supplement, medication, treatment, or testing plan.

Short answer

Test first. Vegans and anyone over 50 should get a level checked and will probably need to supplement. Peter Attia takes methylcobalamin in his own protocol to keep homocysteine down, and Mark Hyman ties a low B12 level to depression, dementia and neuropathy.

Leaning for

Vitamin B12 supplements are worth taking.

The verdict on Vitamin B12 overall. 10 sources: 1 positive, 9 partly

What the evidence says

positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.

  1. Leaning for

    Vegans and people over 50 usually need to supplement B12.

    5 sources: 5 partly.

    Researchers say

    5 partly

    Studies show

    No study counted yet.

    10 more not counted · see why
    We could not confirm who is speaking. 5
    We could not tell where the evidence comes from. 2
    We could not tell what position it takes on this claim. 2
    A host's remark inside an interview. 1
    Show the receipts from 5 sources
    1. Giles Yeo, on The Diary Of A CEO, at 1:09:54 Video · partly · Opinion

      “you have to supplement when you're on a plant-based diet okay you have to supplement certain things vitamin B12”

    2. Mark Hyman Video · partly · 2 mentions

      on The Dr. Hyman Show, at 09:59 · partly · Opinion

      “zinc iron vitamin D B12 omega-3 fats these are the common deficiencies we see in vegans so you have to take”

      on The Dr. Hyman Show, at 47:34 · partly · Opinion

      “older in your vegan it's a problem because you a lot of people have a we call atrophic gastritis they may not absorb B12”

    3. Rahul Jandial, on Rangan Chatterjee's channel, at 03:48 Video · partly · Opinion

      “They can supplement if they're choosing to go vegan. They you recommend they supplement with something containing and B vitamins”

    4. Tommy Wood, on Rangan Chatterjee's channel, at 12:04 Video · partly · Opinion

      “plant-based, I think the best people who uh promote or work with individuals with those diets would recommend you take a B12 supplement”

    5. Dr. Gabrielle Lyon, on Huberman Lab, at 2:29:23 Video · partly · Opinion

      “as individual's age a a vegan diet can be very challenging need to make sure that you are getting enough B12 zinc iron”

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Detailed Answer

Vegans and older adults usually need to supplement B12, but test before you buy. Peter Attia takes methylcobalamin in his own protocol to keep homocysteine down. Mark Hyman pushes hardest on B12 and ties a low level to depression, dementia and neuropathy.

Who should get a level checked

Four groups should test. Vegans get none from food, and absorption drops for anyone over 50. Acid blockers (PPIs) deplete B12, and anyone with an MTHFR variant needs the methylated form, as Rhonda Patrick says.

Which form

Buy methylcobalamin, not cyanocobalamin. Attia and Patrick both land on the methylated form.

Related Questions

What form of B12 is best?
Methylcobalamin, the methylated form, is recommended over cyanocobalamin wherever B12 form comes up.

More Questions About Vitamin B12

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