Expert Answer
Do you need B12 supplements?
Quick Answer
Test first. Attia includes methylcobalamin in his personal protocol for homocysteine management. Hyman links B12 deficiency to depression, dementia, and neuropathy. Vegans and anyone over 50 should test and likely supplement.
Moderate Consensus
on Vitamin B12 overall
What Researchers Say
Includes methylcobalamin in personal protocol specifically for homocysteine management.
Links B12 deficiency to depression, dementia, and neuropathy. Strongest advocate across dozens of videos.
Covers B12 in context of genetics and MTHFR polymorphisms. Recommends methylated form.
Detailed Answer
B12 supplementation depends on your status. Attia includes methylcobalamin in his personal protocol for homocysteine management. Hyman is the strongest advocate, linking deficiency to depression, dementia, and neuropathy.
Key populations who need testing: vegans (no dietary B12), anyone over 50 (absorption declines), people on acid-blocking medications (PPIs deplete B12), and those with MTHFR polymorphisms (Patrick recommends methylated form).
Use methylcobalamin or methylB12, not cyanocobalamin. All experts who discuss B12 insist on the methylated form.
Related Questions
What form of B12 is best?
Methylcobalamin (methylated form). All experts who discuss B12 recommend this over cyanocobalamin.
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