Timing Protocol
Expert-analyzed timing recommendations for hrt & menopause based on what top longevity researchers say about when, how, and what to take it with.
Quick Timing Guide
The 'timing hypothesis' — experts favor starting near menopause onset (broadly within ~10 years), and starting when perimenopausal symptoms begin rather than waiting for a formal menopause definition.
Strong Consensus
on HRT & Menopause overall
Timing
The 'timing hypothesis' — experts favor starting near menopause onset (broadly within ~10 years), and starting when perimenopausal symptoms begin rather than waiting for a formal menopause definition.
Dosage
Prescription-only and individualized — there is no self-administered 'dose.' Experts describe HRT as titrated to symptoms and labs by a menopause-trained clinician, not a fixed protocol.
Form
Where experts express a preference, it's bioidentical: transdermal estradiol (patch/gel/spray) for systemic estrogen, plus micronized (oral) progesterone for women with an intact uterus. Low-dose vaginal estrogen is a separate, lower-risk option for genitourinary symptoms.
Notes
This block summarizes what the experts describe on video about forms and timing — it is educational, not a prescription. Route, formulation, dose, and candidacy are physician decisions, and the calculus changes for women with a history of hormone-sensitive cancer, clotting disorders, or liver disease.
Timing consensus based on knowledge base analysis. Detailed expert deep dives are available for supplements with dedicated reports.
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