Answer

Does NAC boost glutathione levels?

NAC nac glutathione detox

Verdict

Not enough evidence

NAC raises glutathione levels in the body.

1 source: 1 positive

1 source: 1 positive

By Arun AgrahriLast reviewed

Based on what researchers say in public interviews on YouTube. Educational only, not medical advice. Ask a qualified clinician before changing a supplement, medication, treatment, or testing plan.

Short answer

Yes. NAC is a building block for glutathione, which Mark Hyman calls probably the most important molecule in your body. In one person's tracking, glutathione levels dropped measurably after stopping NAC. The dose: 600-1,800mg daily.

Not enough evidence

NAC is worth taking.

The verdict on NAC overall. 2 sources: 2 positive

What the evidence says

positive partly neutral negative Each researcher and each study counts once per claim, however often they come up.

  1. Not enough evidence

    NAC raises glutathione levels in the body.

    1 source: 1 positive. Fewer than 3 sources so far.

    Researchers say

    1 positive

    Studies show

    No study counted yet.

    15 more not counted · see why
    Show the receipts from 1 source
    1. Mark Hyman Video · positive · 9 mentions

      on The Dr. Hyman Show, at 17:35 · positive · Opinion

      “it's the building block of glutathione”

      on The Dr. Hyman Show, at 02:14 · positive · Opinion

      “a special molecule called Knack or NAC that boost your body's own glutathione”

      on The Dr. Hyman Show, at 07:57 · positive · Opinion

      “you can help make more of it when you take certain supplements including an acetylcysteine”

      on The Dr. Hyman Show, at 16:02 · positive · Opinion

      “glutathion boosting stuff netl cysteine lipoic acid milk thisle”

      on The Dr. Hyman Show, at 08:20 · positive · Opinion

      “my glutathion levels is the most important thing I do every day for my health so first one I use is something called n acetylcysteine”

      on Huberman Lab, at 2:16:01 · positive · Opinion

      “So we talked about an acetylcysteine. So anything that boosts glutathione lipoic acid”

      on The Dr. Hyman Show, at 16:26 · positive · Opinion

      “glutathione boosting stuff and acetylcysteine lipoic acid milk thistle”

      on The Dr. Hyman Show, at 11:41 · positive · Opinion

      “it's the building block of glutathione”

      on The Dr. Hyman Show, at 29:34 · positive · Opinion

      “you can help make more of it when you take certain supplements including an acetyl cysteine”

Precis is not affiliated with or endorsed by YouTube or by any researcher, show or publisher we quote. We take no sponsorship, ad or affiliate money, and every verdict is our own review of what was said. How we stay independent

Detailed Answer

NAC raises glutathione levels in the body. It supplies cysteine, the limiting ingredient your body needs to build glutathione. Mark Hyman, on his own show, pushes it hardest.

He has covered NAC across 24 videos and calls glutathione probably the most important molecule in your body, for detox and immune defense. Roger Seheult, in a guest interview, backs the same link.

A biomarker read

Bryan Johnson has the cleanest biomarker read. His glutathione levels dropped when he cycled off NAC, and he keeps it as a core daily pill.

Pairings

NAC goes with zinc for immune support and cold prevention, and with alpha-lipoic acid, B vitamins, selenium and milk thistle for detox.

Related Questions

Is NAC still available as a supplement?
The FDA raised concerns in 2021 about NAC's supplement status, but it remains widely available. Regulatory status may vary by region.

More Questions About NAC

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